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Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors

Introduction of heterologous anti–glomerular basement membrane antiserum (nephrotoxic serum, NTS) into presensitized mice triggers the production of IgG anti-NTS antibodies that are predominantly IgG2b and the glomerular deposition of pathogenic immune complexes, leading to accelerated renal disease...

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Detalles Bibliográficos
Autores principales: Kaneko, Yoshikatsu, Nimmerjahn, Falk, Madaio, Michael P., Ravetch, Jeffrey V.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118246/
https://www.ncbi.nlm.nih.gov/pubmed/16520389
http://dx.doi.org/10.1084/jem.20051900