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Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells

Oral tolerance induction is a key feature of intestinal immunity, generating systemic nonresponsiveness to ingested antigens. In this study, we report that orally applied soluble antigens are exclusively recognized in the intestinal immune system, particularly in the mesenteric lymph nodes. Conseque...

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Detalles Bibliográficos
Autores principales: Worbs, Tim, Bode, Ulrike, Yan, Sheng, Hoffmann, Matthias W., Hintzen, Gabriele, Bernhardt, Günter, Förster, Reinhold, Pabst, Oliver
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118247/
https://www.ncbi.nlm.nih.gov/pubmed/16533884
http://dx.doi.org/10.1084/jem.20052016