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Systemic antithrombotic effects of ADAMTS13

The metalloprotease ADAMTS13 (a disintegrin-like and metalloprotease with thrombospondin type I repeats 13) cleaves highly adhesive large von Willebrand factor (VWF) multimers after their release from the endothelium. ADAMTS13 deficiency is linked to a life-threatening disorder, thrombotic thrombocy...

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Detalles Bibliográficos
Autores principales: Chauhan, Anil K., Motto, David G., Lamb, Colin B., Bergmeier, Wolfgang, Dockal, Michael, Plaimauer, Barbara, Scheiflinger, Friedrich, Ginsburg, David, Wagner, Denisa D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118248/
https://www.ncbi.nlm.nih.gov/pubmed/16533881
http://dx.doi.org/10.1084/jem.20051732