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The primary defect in experimental ileitis originates from a nonhematopoietic source

The initiating etiologic factor in Crohn's disease (CD) remains unclear. SAMP1/YitFc (SAMP) mice develop chronic ileitis similar to human CD. We used bone marrow chimeras to determine if SAMP ileitis results from a primary immunological defect or from dysregulated mucosal immunity secondary to...

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Detalles Bibliográficos
Autores principales: Olson, Timothy S., Reuter, Brian K., Scott, Kevin G-E., Morris, Margaret A., Wang, Xiao-Ming, Hancock, Leslie N., Burcin, Tracy L., Cohn, Steven M., Ernst, Peter B., Cominelli, Fabio, Meddings, Jonathan B., Ley, Klaus, Pizarro, Theresa T.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118253/
https://www.ncbi.nlm.nih.gov/pubmed/16505137
http://dx.doi.org/10.1084/jem.20050407