Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation

B cells responding to T-dependent antigen either differentiate rapidly into extrafollicular plasma cells or enter germinal centers and undergo somatic hypermutation and affinity maturation. However, the physiological cues that direct B cell differentiation down one pathway versus the other are unkno...

Descripción completa

Detalles Bibliográficos
Autores principales: Paus, Didrik, Phan, Tri Giang, Chan, Tyani D., Gardam, Sandra, Basten, Antony, Brink, Robert
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118299/
https://www.ncbi.nlm.nih.gov/pubmed/16606676
http://dx.doi.org/10.1084/jem.20060087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118299/
https://www.ncbi.nlm.nih.gov/pubmed/16606676
http://dx.doi.org/10.1084/jem.20060087

Ejemplares similares