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Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation

B cells responding to T-dependent antigen either differentiate rapidly into extrafollicular plasma cells or enter germinal centers and undergo somatic hypermutation and affinity maturation. However, the physiological cues that direct B cell differentiation down one pathway versus the other are unkno...

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Detalles Bibliográficos
Autores principales:	Paus, Didrik, Phan, Tri Giang, Chan, Tyani D., Gardam, Sandra, Basten, Antony, Brink, Robert
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2006
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118299/ https://www.ncbi.nlm.nih.gov/pubmed/16606676 http://dx.doi.org/10.1084/jem.20060087

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