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B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma

Tumor-associated macrophages are a prominent component of ovarian cancer stroma and contribute to tumor progression. B7-H4 is a recently identified B7 family molecule. We show that primary ovarian tumor cells express intracellular B7-H4, whereas a fraction of tumor macrophages expresses surface B7-H...

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Detalles Bibliográficos
Autores principales: Kryczek, Ilona, Zou, Linhua, Rodriguez, Paulo, Zhu, Gefeng, Wei, Shuang, Mottram, Peter, Brumlik, Michael, Cheng, Pui, Curiel, Tyler, Myers, Leann, Lackner, Andrew, Alvarez, Xavier, Ochoa, Augusto, Chen, Lieping, Zou, Weiping
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118300/
https://www.ncbi.nlm.nih.gov/pubmed/16606666
http://dx.doi.org/10.1084/jem.20050930