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Postnatal acquisition of endotoxin tolerance in intestinal epithelial cells

The role of innate immune recognition by intestinal epithelial cells (IECs) in vivo is ill-defined. Here, we used highly enriched primary IECs to analyze Toll-like receptor (TLR) signaling and mechanisms that prevent inappropriate stimulation by the colonizing microflora. Although the lipopolysaccha...

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Detalles Bibliográficos
Autores principales: Lotz, Michael, Gütle, Dominique, Walther, Sabrina, Ménard, Sandrine, Bogdan, Christian, Hornef, Mathias W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118301/
https://www.ncbi.nlm.nih.gov/pubmed/16606665
http://dx.doi.org/10.1084/jem.20050625