Cargando…
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4(+) T reg cells
Regulatory T (T reg) cells are critical regulators of immune tolerance. Most T reg cells are defined based on expression of CD4, CD25, and the transcription factor, FoxP3. However, these markers have proven problematic for uniquely defining this specialized T cell subset in humans. We found that the...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118339/ https://www.ncbi.nlm.nih.gov/pubmed/16818678 http://dx.doi.org/10.1084/jem.20060772 |