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CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4(+) T reg cells
Regulatory T (T reg) cells are critical regulators of immune tolerance. Most T reg cells are defined based on expression of CD4, CD25, and the transcription factor, FoxP3. However, these markers have proven problematic for uniquely defining this specialized T cell subset in humans. We found that the...
Autores principales: | Liu, Weihong, Putnam, Amy L., Xu-yu, Zhou, Szot, Gregory L., Lee, Michael R., Zhu, Shirley, Gottlieb, Peter A., Kapranov, Philipp, Gingeras, Thomas R., de St. Groth, Barbara Fazekas, Clayberger, Carol, Soper, David M., Ziegler, Steven F., Bluestone, Jeffrey A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118339/ https://www.ncbi.nlm.nih.gov/pubmed/16818678 http://dx.doi.org/10.1084/jem.20060772 |
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