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Role of HMGB1 in apoptosis-mediated sepsis lethality

Severe sepsis, a lethal syndrome after infection or injury, is the third leading cause of mortality in the United States. The pathogenesis of severe sepsis is characterized by organ damage and accumulation of apoptotic lymphocytes in the spleen, thymus, and other organs. To examine the potential cau...

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Detalles Bibliográficos
Autores principales: Qin, Shixin, Wang, Haichao, Yuan, Renqi, Li, Hui, Ochani, Mahendar, Ochani, Kanta, Rosas-Ballina, Mauricio, Czura, Chris J., Huston, Jared M., Miller, Ed, Lin, Xinchun, Sherry, Barbara, Kumar, Anjali, LaRosa, Greg, Newman, Walter, Tracey, Kevin J., Yang, Huan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118346/
https://www.ncbi.nlm.nih.gov/pubmed/16818669
http://dx.doi.org/10.1084/jem.20052203