Critical roles of the immunoglobulin intronic enhancers in maintaining the sequential rearrangement of IgH and Igk loci

V(D)J recombination of immunoglobulin (Ig) heavy (IgH) and light chain genes occurs sequentially in the pro– and pre–B cells. To identify cis-elements that dictate this order of rearrangement, we replaced the endogenous matrix attachment region/Igk intronic enhancer (MiE(κ)) with its heavy chain cou...

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Detalles Bibliográficos
Autores principales: Inlay, Matthew A., Lin, Tongxiang, Gao, Heather H., Xu, Yang
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118354/
https://www.ncbi.nlm.nih.gov/pubmed/16785310
http://dx.doi.org/10.1084/jem.20052310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118354/
https://www.ncbi.nlm.nih.gov/pubmed/16785310
http://dx.doi.org/10.1084/jem.20052310

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