T-bet negatively regulates autoimmune myocarditis by suppressing local production of interleukin 17

Experimental autoimmune myocarditis (EAM) appears after infectious heart disease, the most common cause of dilated cardiomyopathy in humans. Here we report that mice lacking T-bet, a T-box transcription factor required for T helper (Th)1 cell differentiation and interferon (IFN)-γ production, develo...

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Detalles Bibliográficos
Autores principales: Rangachari, Manu, Mauermann, Nora, Marty, René R., Dirnhofer, Stephan, Kurrer, Michael O., Komnenovic, Vukoslav, Penninger, Josef M., Eriksson, Urs
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118365/
https://www.ncbi.nlm.nih.gov/pubmed/16880257
http://dx.doi.org/10.1084/jem.20052222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118365/
https://www.ncbi.nlm.nih.gov/pubmed/16880257
http://dx.doi.org/10.1084/jem.20052222

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