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Neutrophils from p40(phox−/−) mice exhibit severe defects in NADPH oxidase regulation and oxidant-dependent bacterial killing
The generation of reactive oxygen species (ROS) by the reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex plays a critical role in the antimicrobial functions of the phagocytic cells of the immune system. The catalytic core of this oxidase consists of a complex between gp91(...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118373/ https://www.ncbi.nlm.nih.gov/pubmed/16880254 http://dx.doi.org/10.1084/jem.20052069 |