The phosphoinositide-binding protein p40(phox) activates the NADPH oxidase during FcγIIA receptor–induced phagocytosis

Superoxide produced by the phagocyte reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase is essential for host defense. Enzyme activation requires translocation of p67(phox), p47(phox), and Rac-GTP to flavocytochrome b (558) in phagocyte membranes. To examine the regulation of phagoc...

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Detalles Bibliográficos
Autores principales: Suh, Chang-Il, Stull, Natalie D., Li, Xing Jun, Tian, Wei, Price, Marianne O., Grinstein, Sergio, Yaffe, Michael B., Atkinson, Simon, Dinauer, Mary C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118377/
https://www.ncbi.nlm.nih.gov/pubmed/16880255
http://dx.doi.org/10.1084/jem.20052085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118377/
https://www.ncbi.nlm.nih.gov/pubmed/16880255
http://dx.doi.org/10.1084/jem.20052085

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