Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction

Immune mechanisms have been implicated in placental dysfunction in patients with recurrent miscarriages and intrauterine growth restriction (IUGR), but the mediators are undefined. Here we show that complement activation, particularly C5a, is a required intermediary event in the pathogenesis of plac...

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Detalles Bibliográficos
Autores principales: Girardi, Guillermina, Yarilin, Dmitry, Thurman, Joshua M., Holers, V. Michael, Salmon, Jane E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2006
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118387/
https://www.ncbi.nlm.nih.gov/pubmed/16923853
http://dx.doi.org/10.1084/jem.20061022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118387/
https://www.ncbi.nlm.nih.gov/pubmed/16923853
http://dx.doi.org/10.1084/jem.20061022

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