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Complement activation induces dysregulation of angiogenic factors and causes fetal rejection and growth restriction
Immune mechanisms have been implicated in placental dysfunction in patients with recurrent miscarriages and intrauterine growth restriction (IUGR), but the mediators are undefined. Here we show that complement activation, particularly C5a, is a required intermediary event in the pathogenesis of plac...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118387/ https://www.ncbi.nlm.nih.gov/pubmed/16923853 http://dx.doi.org/10.1084/jem.20061022 |