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Duration of the initial TCR stimulus controls the magnitude but not functionality of the CD8(+) T cell response
CD8(+) T cells only require a brief stimulation with antigen in vitro to divide and differentiate into effector and memory cells upon transfer in vivo. The efficiency of clonal expansion and the functional characteristics of memory cells derived from briefly stimulated cells are poorly defined. We d...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118397/ https://www.ncbi.nlm.nih.gov/pubmed/16908626 http://dx.doi.org/10.1084/jem.20060928 |