An essential role for RasGRP1 in mast cell function and IgE-mediated allergic response

Cross-linking of the FcɛRI activates the phosphatidyl inositol 3 kinase (PI3K) and mitogen-activated protein kinase pathways. Previous studies demonstrate that Ras guanyl nucleotide-releasing protein (RasGRP)1 is essential in T cell receptor–mediated Ras-Erk activation. Here, we report that RasGRP1...

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Detalles Bibliográficos
Autores principales: Liu, Yan, Zhu, Minghua, Nishida, Keigo, Hirano, Toshio, Zhang, Weiguo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118421/
https://www.ncbi.nlm.nih.gov/pubmed/17190838
http://dx.doi.org/10.1084/jem.20061598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118421/
https://www.ncbi.nlm.nih.gov/pubmed/17190838
http://dx.doi.org/10.1084/jem.20061598

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