Mechanism of thioamide drug action against tuberculosis and leprosy

Thioamide drugs, ethionamide (ETH) and prothionamide (PTH), are clinically effective in the treatment of Mycobacterium tuberculosis, M. leprae, and M. avium complex infections. Although generally considered second-line drugs for tuberculosis, their use has increased considerably as the number of mul...

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Detalles Bibliográficos
Autores principales: Wang, Feng, Langley, Robert, Gulten, Gulcin, Dover, Lynn G., Besra, Gurdyal S., Jacobs, William R., Sacchettini, James C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118422/
https://www.ncbi.nlm.nih.gov/pubmed/17227913
http://dx.doi.org/10.1084/jem.20062100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118422/
https://www.ncbi.nlm.nih.gov/pubmed/17227913
http://dx.doi.org/10.1084/jem.20062100

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