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Mechanism of thioamide drug action against tuberculosis and leprosy
Thioamide drugs, ethionamide (ETH) and prothionamide (PTH), are clinically effective in the treatment of Mycobacterium tuberculosis, M. leprae, and M. avium complex infections. Although generally considered second-line drugs for tuberculosis, their use has increased considerably as the number of mul...
Autores principales: | Wang, Feng, Langley, Robert, Gulten, Gulcin, Dover, Lynn G., Besra, Gurdyal S., Jacobs, William R., Sacchettini, James C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118422/ https://www.ncbi.nlm.nih.gov/pubmed/17227913 http://dx.doi.org/10.1084/jem.20062100 |
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