Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals

Although required for many fundamental immune processes, ranging from self-tolerance to pathogen immunity, interleukin (IL)-2 production is transient, and the mechanisms underlying this brevity remain unclear. These studies reveal that helper T cell IL-2 production is limited by a classic negative f...

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Detalles Bibliográficos
Autores principales: Villarino, Alejandro V., Tato, Cristina M., Stumhofer, Jason S., Yao, Zhengju, Cui, Yongzhi K., Hennighausen, Lothar, O'Shea, John J., Hunter, Christopher A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118423/
https://www.ncbi.nlm.nih.gov/pubmed/17227909
http://dx.doi.org/10.1084/jem.20061198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118423/
https://www.ncbi.nlm.nih.gov/pubmed/17227909
http://dx.doi.org/10.1084/jem.20061198

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