Dendritic cell–expanded, islet-specific CD4(+) CD25(+) CD62L(+) regulatory T cells restore normoglycemia in diabetic NOD mice

Most treatments that prevent autoimmune diabetes in nonobese diabetic (NOD) mice require intervention at early pathogenic stages, when insulitis is first developing. We tested whether dendritic cell (DC)–expanded, islet antigen–specific CD4(+) CD25(+) suppressor T cells could treat diabetes at later...

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Detalles Bibliográficos
Autores principales: Tarbell, Kristin V., Petit, Lucine, Zuo, Xiaopan, Toy, Priscilla, Luo, Xunrong, Mqadmi, Amina, Yang, Hua, Suthanthiran, Manikkam, Mojsov, Svetlana, Steinman, Ralph M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118426/
https://www.ncbi.nlm.nih.gov/pubmed/17210729
http://dx.doi.org/10.1084/jem.20061631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118426/
https://www.ncbi.nlm.nih.gov/pubmed/17210729
http://dx.doi.org/10.1084/jem.20061631

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