Induced sensitization of tumor stroma leads to eradication of established cancer by T cells

Targeting cancer cells, as well as the nonmalignant stromal cells cross-presenting the tumor antigen (Ag), can lead to the complete destruction of well-established solid tumors by adoptively transferred Ag-specific cytotoxic T lymphocytes (CTLs). If, however, cancer cells express only low levels of...

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Detalles Bibliográficos
Autores principales: Zhang, Bin, Bowerman, Natalie A., Salama, Joseph K., Schmidt, Hank, Spiotto, Michael T., Schietinger, Andrea, Yu, Ping, Fu, Yang-Xin, Weichselbaum, Ralph R., Rowley, Donald A., Kranz, David M., Schreiber, Hans
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118433/
https://www.ncbi.nlm.nih.gov/pubmed/17210731
http://dx.doi.org/10.1084/jem.20062056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118433/
https://www.ncbi.nlm.nih.gov/pubmed/17210731
http://dx.doi.org/10.1084/jem.20062056

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