High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells

The best-characterized type 1 interferon (IFN) signaling pathway depends on signal transducer and activator of transcription 1 (STAT1) and STAT2. The cytokines can, however, conditionally activate all STATs. Regulation of their access to particular signaling pathways is poorly understood. STAT4 is i...

Descripción completa

Detalles Bibliográficos
Autores principales: Miyagi, Takuya, Gil, M. Pilar, Wang, Xin, Louten, Jennifer, Chu, Wen-Ming, Biron, Christine A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118450/
https://www.ncbi.nlm.nih.gov/pubmed/17846149
http://dx.doi.org/10.1084/jem.20070401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118450/
https://www.ncbi.nlm.nih.gov/pubmed/17846149
http://dx.doi.org/10.1084/jem.20070401

Ejemplares similares