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Cdc42-interacting protein–4 functionally links actin and microtubule networks at the cytolytic NK cell immunological synapse

An essential function of the immunological synapse (IS) is directed secretion. NK cells are especially adept at this activity, as they direct lytic granules to the synapse for secretion, which enables cytotoxicity and facilitates host defense. This initially requires rearrangement of the actin cytos...

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Detalles Bibliográficos
Autores principales: Banerjee, Pinaki P., Pandey, Rahul, Zheng, Rena, Suhoski, Megan M., Monaco-Shawver, Linda, Orange, Jordan S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118451/
https://www.ncbi.nlm.nih.gov/pubmed/17785506
http://dx.doi.org/10.1084/jem.20061893