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Cdc42-interacting protein–4 functionally links actin and microtubule networks at the cytolytic NK cell immunological synapse
An essential function of the immunological synapse (IS) is directed secretion. NK cells are especially adept at this activity, as they direct lytic granules to the synapse for secretion, which enables cytotoxicity and facilitates host defense. This initially requires rearrangement of the actin cytos...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118451/ https://www.ncbi.nlm.nih.gov/pubmed/17785506 http://dx.doi.org/10.1084/jem.20061893 |