Reexpression of caveolin-1 in endothelium rescues the vascular, cardiac, and pulmonary defects in global caveolin-1 knockout mice

Caveolin-1 (Cav-1) is the principal structural component of caveolae organelles in smooth muscle cells, adipocytes, fibroblasts, epithelial cells, and endothelial cells (ECs). Cav-1–deficient (Cav-1 knockout [KO]) mice are viable and show increases of nitric oxide (NO) production in vasculature, car...

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Detalles Bibliográficos
Autores principales: Murata, Takahisa, Lin, Michelle I., Huang, Yan, Yu, Jun, Bauer, Phillip Michael, Giordano, Frank J., Sessa, William C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118452/
https://www.ncbi.nlm.nih.gov/pubmed/17893196
http://dx.doi.org/10.1084/jem.20062340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118452/
https://www.ncbi.nlm.nih.gov/pubmed/17893196
http://dx.doi.org/10.1084/jem.20062340

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