Autocrine/paracrine TGFβ1 is required for the development of epidermal Langerhans cells

Langerhans cells (LCs) are bone marrow (BM)–derived epidermal dendritic cells (DCs) that develop from precursors found in the dermis. Epidermal LCs are absent in transforming growth factor (TGF) β1-deficient mice. It is not clear whether TGFβ1 acts directly on LC precursors to promote maturation or...

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Detalles Bibliográficos
Autores principales: Kaplan, Daniel H., Li, Ming O., Jenison, Matthew C., Shlomchik, Warren D., Flavell, Richard A., Shlomchik, Mark J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118472/
https://www.ncbi.nlm.nih.gov/pubmed/17938236
http://dx.doi.org/10.1084/jem.20071401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118472/
https://www.ncbi.nlm.nih.gov/pubmed/17938236
http://dx.doi.org/10.1084/jem.20071401

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