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Detuning CD8 T cells: down-regulation of CD8 expression, tetramer binding, and response during CTL activation
CD8 is critical for T cell recognition of peptide/class I major histocompatability complex ligands, yet is down-regulated during activation of CD8 T cells. We report that loss of CD8 expression early during in vivo responses to vaccinia virus or Listeria monocytogenes (LM) correlates with decreased...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118473/ https://www.ncbi.nlm.nih.gov/pubmed/17954566 http://dx.doi.org/10.1084/jem.20062376 |