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Detuning CD8 T cells: down-regulation of CD8 expression, tetramer binding, and response during CTL activation

CD8 is critical for T cell recognition of peptide/class I major histocompatability complex ligands, yet is down-regulated during activation of CD8 T cells. We report that loss of CD8 expression early during in vivo responses to vaccinia virus or Listeria monocytogenes (LM) correlates with decreased...

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Detalles Bibliográficos
Autores principales:	Xiao, Zhengguo, Mescher, Matthew F., Jameson, Stephen C.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2007
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118473/ https://www.ncbi.nlm.nih.gov/pubmed/17954566 http://dx.doi.org/10.1084/jem.20062376

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