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T cell activation enhancement by endogenous pMHC acts for both weak and strong agonists but varies with differentiation state
T cells are extremely sensitive in their ability to find minute amounts of antigenic peptide in the midst of many endogenous peptides presented on an antigen-presenting cell. The role of endogenous peptides in the recognition of foreign peptide and hence in T cell activation has remained controversi...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118480/ https://www.ncbi.nlm.nih.gov/pubmed/17954567 http://dx.doi.org/10.1084/jem.20062610 |