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Induction of high-affinity IgE receptor on lung dendritic cells during viral infection leads to mucous cell metaplasia

Respiratory viral infections are associated with an increased risk of asthma, but how acute Th1 antiviral immune responses lead to chronic inflammatory Th2 disease remains undefined. We define a novel pathway that links transient viral infection to chronic lung disease with dendritic cell (DC) expre...

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Detalles Bibliográficos
Autores principales: Grayson, Mitchell H., Cheung, Dorothy, Rohlfing, Michelle M., Kitchens, Robert, Spiegel, Daniel E., Tucker, Jennifer, Battaile, John T., Alevy, Yael, Yan, Le, Agapov, Eugene, Kim, Edy Y., Holtzman, Michael J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118483/
https://www.ncbi.nlm.nih.gov/pubmed/17954569
http://dx.doi.org/10.1084/jem.20070360