AIDS virus–specific CD8(+) T lymphocytes against an immunodominant cryptic epitope select for viral escape

Cryptic major histocompatibility complex class I epitopes have been detected in several pathogens, but their importance in the immune response to AIDS viruses remains unknown. Here, we show that Mamu-B*17 (+) simian immunodeficiency virus (SIV)mac239-infected rhesus macaques that spontaneously contr...

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Detalles Bibliográficos
Autores principales: Maness, Nicholas J., Valentine, Laura E., May, Gemma E., Reed, Jason, Piaskowski, Shari M., Soma, Taeko, Furlott, Jessica, Rakasz, Eva G., Friedrich, Thomas C., Price, David A., Gostick, Emma, Hughes, Austin L., Sidney, John, Sette, Alessandro, Wilson, Nancy A., Watkins, David I.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Brief Definitive Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118485/
https://www.ncbi.nlm.nih.gov/pubmed/17954573
http://dx.doi.org/10.1084/jem.20071261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118485/
https://www.ncbi.nlm.nih.gov/pubmed/17954573
http://dx.doi.org/10.1084/jem.20071261

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