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AIDS virus–specific CD8(+) T lymphocytes against an immunodominant cryptic epitope select for viral escape
Cryptic major histocompatibility complex class I epitopes have been detected in several pathogens, but their importance in the immune response to AIDS viruses remains unknown. Here, we show that Mamu-B*17 (+) simian immunodeficiency virus (SIV)mac239-infected rhesus macaques that spontaneously contr...
Autores principales: | Maness, Nicholas J., Valentine, Laura E., May, Gemma E., Reed, Jason, Piaskowski, Shari M., Soma, Taeko, Furlott, Jessica, Rakasz, Eva G., Friedrich, Thomas C., Price, David A., Gostick, Emma, Hughes, Austin L., Sidney, John, Sette, Alessandro, Wilson, Nancy A., Watkins, David I. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118485/ https://www.ncbi.nlm.nih.gov/pubmed/17954573 http://dx.doi.org/10.1084/jem.20071261 |
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