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Molecular mechanism of mast cell–mediated innate defense against endothelin and snake venom sarafotoxin

Mast cells are protective against snake venom sarafotoxins that belong to the endothelin (ET) peptide family. The molecular mechanism underlying this recently recognized innate defense pathway is unknown, but secretory granule proteases have been invoked. To specifically disrupt a single protease fu...

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Detalles Bibliográficos
Autores principales: Schneider, Lars A., Schlenner, Susan M., Feyerabend, Thorsten B., Wunderlin, Markus, Rodewald, Hans-Reimer
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118486/
https://www.ncbi.nlm.nih.gov/pubmed/17923505
http://dx.doi.org/10.1084/jem.20071262