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A constant affinity threshold for T cell tolerance

T cell tolerance depends on the T cell receptor's affinity for peptide/major histocompatibility complex (MHC) ligand; this critical parameter determines whether a thymocyte will be included (positive selection) or excluded (negative selection) from the T cell repertoire. A quantitative analysis...

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Detalles Bibliográficos
Autores principales: Naeher, Dieter, Daniels, Mark A., Hausmann, Barbara, Guillaume, Philippe, Luescher, Immanuel, Palmer, Ed
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118488/
https://www.ncbi.nlm.nih.gov/pubmed/17938233
http://dx.doi.org/10.1084/jem.20070254