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LPS-induced down-regulation of signal regulatory protein α contributes to innate immune activation in macrophages

Activation of the mitogen-activated protein kinases (MAPKs) and nuclear factor κB (NF-κB) cascades after Toll-like receptor (TLR) stimulation contributes to innate immune responses. Signal regulatory protein (SIRP) α, a member of the SIRP family that is abundantly expressed in macrophages, has been...

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Detalles Bibliográficos
Autores principales: Kong, Xiao-Ni, Yan, He-Xin, Chen, Lei, Dong, Li-Wei, Yang, Wen, Liu, Qiong, Yu, Le-Xing, Huang, Dan-Dan, Liu, Shu-Qin, Liu, Hui, Wu, Meng-Chao, Wang, Hong-Yang
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118489/
https://www.ncbi.nlm.nih.gov/pubmed/17954568
http://dx.doi.org/10.1084/jem.20062611