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New lane in the information highway: alternative reading frame peptides elicit T cells with potent antiretrovirus activity
CD8(+) T cells rapidly recognize virus-infected cells due to the generation of antigenic peptides from defective ribosomal products (DRiPs) that are encoded by standard open reading frames (ORFs). New data now show that alternative reading frame (ARF) DRiPs can also induce robust CD8(+) T cell respo...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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The Rockefeller University Press
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118496/ https://www.ncbi.nlm.nih.gov/pubmed/17954574 http://dx.doi.org/10.1084/jem.20071986 |