Facilitation of Th1-mediated immune response by prostaglandin E receptor EP1

Prostaglandin E(2) (PGE(2)) exerts its actions via four subtypes of the PGE receptor, EP1–4. We show that mice deficient in EP1 exhibited significantly attenuated Th1 response in contact hypersensitivity induced by dinitrofluorobenzene (DNFB). This phenotype was recapitulated in wild-type mice by ad...

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Detalles Bibliográficos
Autores principales: Nagamachi, Miyako, Sakata, Daiji, Kabashima, Kenji, Furuyashiki, Tomoyuki, Murata, Takahiko, Segi-Nishida, Eri, Soontrapa, Kitipong, Matsuoka, Toshiyuki, Miyachi, Yoshiki, Narumiya, Shuh
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118516/
https://www.ncbi.nlm.nih.gov/pubmed/17967902
http://dx.doi.org/10.1084/jem.20070773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118516/
https://www.ncbi.nlm.nih.gov/pubmed/17967902
http://dx.doi.org/10.1084/jem.20070773

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