Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis

Cell proliferation is strictly controlled during differentiation. In T cell development, the cell cycle is normally arrested at the CD4(+)CD8(+) stage, but the mechanism underlying such differentiation-specific exit from the cell cycle has been unclear. Fbxw7 (also known as Fbw7, Sel-10, hCdc4, or h...

Descripción completa

Detalles Bibliográficos
Autores principales: Onoyama, Ichiro, Tsunematsu, Ryosuke, Matsumoto, Akinobu, Kimura, Taichi, de Alborán, Ignacio Moreno, Nakayama, Keiko, Nakayama, Keiichi I.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118521/
https://www.ncbi.nlm.nih.gov/pubmed/17984302
http://dx.doi.org/10.1084/jem.20062299

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118521/
https://www.ncbi.nlm.nih.gov/pubmed/17984302
http://dx.doi.org/10.1084/jem.20062299

Ejemplares similares