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Spontaneous tumor rejection by cbl-b–deficient CD8(+) T cells

The concept of tumor surveillance implies that specific and nonspecific components of the immune system eliminate tumors in the early phase of malignancy. Understanding the biochemical mechanisms of tumor immunosurveillance is of paramount significance because it might allow one to specifically modu...

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Detalles Bibliográficos
Autores principales: Loeser, Stefanie, Loser, Karin, Bijker, Martijn S., Rangachari, Manu, van der Burg, Sjoerd H., Wada, Teiji, Beissert, Stefan, Melief, Cornelis J.M., Penninger, Josef M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118550/
https://www.ncbi.nlm.nih.gov/pubmed/17403934
http://dx.doi.org/10.1084/jem.20061699