Frequent and specific immunity to the embryonal stem cell–associated antigen SOX2 in patients with monoclonal gammopathy

Specific targets of cellular immunity in human premalignancy are largely unknown. Monoclonal gammopathy of undetermined significance (MGUS) represents a precursor lesion to myeloma (MM). We show that antigenic targets of spontaneous immunity in MGUS differ from MM. MGUS patients frequently mount a h...

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Detalles Bibliográficos
Autores principales: Spisek, Radek, Kukreja, Anjli, Chen, Lin-Chi, Matthews, Phillip, Mazumder, Amitabha, Vesole, David, Jagannath, Sundar, Zebroski, Henry A., Simpson, Andrew J.G., Ritter, Gerd, Durie, Brian, Crowley, John, Shaughnessy, John D., Scanlan, Matthew J., Gure, Ali O., Barlogie, Bart, Dhodapkar, Madhav V.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118551/
https://www.ncbi.nlm.nih.gov/pubmed/17389240
http://dx.doi.org/10.1084/jem.20062387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118551/
https://www.ncbi.nlm.nih.gov/pubmed/17389240
http://dx.doi.org/10.1084/jem.20062387

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