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Mature natural killer cell and lymphoid tissue–inducing cell development requires Id2-mediated suppression of E protein activity

The Id2 transcriptional repressor is essential for development of natural killer (NK) cells, lymphoid tissue–inducing (LTi) cells, and secondary lymphoid tissues. Id2 was proposed to regulate NK and LTi lineage specification from multipotent progenitors through suppression of E proteins. We report t...

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Detalles Bibliográficos
Autores principales: Boos, Markus D., Yokota, Yoshifumi, Eberl, Gerard, Kee, Barbara L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118569/
https://www.ncbi.nlm.nih.gov/pubmed/17452521
http://dx.doi.org/10.1084/jem.20061959