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Expression of lymphotoxin-αβ on antigen-specific T cells is required for DC function

During an immune response, activated antigen (Ag)-specific T cells condition dendritic cells (DCs) to enhance DC function and survival within the inflamed draining lymph node (LN). It has been difficult to ascertain the role of the tumor necrosis factor (TNF) superfamily member lymphotoxin-αβ (LTαβ)...

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Detalles Bibliográficos
Autores principales: Summers-deLuca, Leslie E., McCarthy, Douglas D., Cosovic, Bojana, Ward, Lesley A., Lo, Calvin C., Scheu, Stefanie, Pfeffer, Klaus, Gommerman, Jennifer L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118582/
https://www.ncbi.nlm.nih.gov/pubmed/17452522
http://dx.doi.org/10.1084/jem.20061968