Cargando…

Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program

The ability of dendritic cells (DCs) to activate immunity is linked to their maturation status. In prior studies, we have shown that selective antibody-mediated blockade of inhibitory FcγRIIB receptor on human DCs in the presence of activating immunoglobulin (Ig) ligands leads to DC maturation and e...

Descripción completa

Detalles Bibliográficos
Autores principales: Dhodapkar, Kavita M., Banerjee, Devi, Connolly, John, Kukreja, Anjli, Matayeva, Elyana, Veri, Maria Concetta, Ravetch, Jeffrey V., Steinman, Ralph M., Dhodapkar, Madhav V.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118610/
https://www.ncbi.nlm.nih.gov/pubmed/17502666
http://dx.doi.org/10.1084/jem.20062545