Type I interferons produced by hematopoietic cells protect mice against lethal infection by mammalian reovirus

We defined the function of type I interferons (IFNs) in defense against reovirus strain type 1 Lang (T1L), which is a double-stranded RNA virus that infects Peyer's patches (PPs) after peroral inoculation of mice. T1L induced expression of mRNA for IFN-α, IFN-β, and Mx-1 in PPs and caused local...

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Detalles Bibliográficos
Autores principales: Johansson, Cecilia, Wetzel, J. Denise, He, JianPing, Mikacenic, Carmen, Dermody, Terence S., Kelsall, Brian L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118611/
https://www.ncbi.nlm.nih.gov/pubmed/17502662
http://dx.doi.org/10.1084/jem.20061587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118611/
https://www.ncbi.nlm.nih.gov/pubmed/17502662
http://dx.doi.org/10.1084/jem.20061587

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