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Increased susceptibility to colitis and colorectal tumors in mice lacking core 3–derived O-glycans
Altered intestinal O-glycan expression has been observed in patients with ulcerative colitis and colorectal cancer, but the role of this alteration in the etiology of these diseases is unknown. O-glycans in mucin core proteins are the predominant components of the intestinal mucus, which comprises p...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118614/ https://www.ncbi.nlm.nih.gov/pubmed/17517967 http://dx.doi.org/10.1084/jem.20061929 |