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Altering the distribution of Foxp3(+) regulatory T cells results in tissue-specific inflammatory disease

CD4(+)Foxp3(+) regulatory T cells (T reg) are essential for maintaining self-tolerance, but their functional mechanisms and sites of action in vivo are poorly defined. We examined the homing receptor expression and tissue distribution of T reg cells in the steady state and determined whether alterin...

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Detalles Bibliográficos
Autores principales: Sather, Blythe D., Treuting, Piper, Perdue, Nikole, Miazgowicz, Mike, Fontenot, Jason D., Rudensky, Alexander Y., Campbell, Daniel J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118615/
https://www.ncbi.nlm.nih.gov/pubmed/17548521
http://dx.doi.org/10.1084/jem.20070081