Cargando…
CTLA-4: From conflict to clinic
CTLA-4 was first identified in 1991 as a second receptor for the T cell costimulation ligand B7. Uncertainties about its biological function plagued the early years after its discovery until 1995, when it was confirmed to be an inhibitor of T cell responses. CTLA-4 has since scored in the clinic as...
Autor principal: | Bashyam, Hema |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118622/ https://www.ncbi.nlm.nih.gov/pubmed/17632849 http://dx.doi.org/10.1084/jem.2046fta |
Ejemplares similares
-
Receptor editing: How B cells stay tolerant
por: Bashyam, Hema
Publicado: (2007) -
Uncovering the dark side of TNF
por: Bashyam, Hema
Publicado: (2007) -
Interleukin-12: A master regulator
por: Bashyam, Hema
Publicado: (2007) -
Lewis Dahl and the genetics of salt-induced hypertension
por: Bashyam, Hema
Publicado: (2007) -
Th1/Th2 cross-regulation and the discovery of IL-10
por: Bashyam, Hema
Publicado: (2007)